GCS-β-2 Polyclonal Antibody

Background:
Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

Alternative Names:
GUCY1B2, Guanylate cyclase soluble subunit beta-2, GCS-beta-2

Immunogen: The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 70

GeneID: GUCY1B2

Storage: -20°C/1 year

NOTE: For Research Use Only