GCS-β-2 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

Synonyms: GUCY1B2, Guanylate cyclase soluble subunit beta-2, GCS-beta-2

Gene Name: GUCY1B2

Gene ID: 2974

SwissProt ID: O75343

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.