GCSH antibody (clone M2), anti-human
€435.00
In stock
SKU
AC-AT2184a
Catalog Number: AC-AT2184a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT2184a">Request Information
Background:
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
Other Names:
Glycine cleavage system H protein, mitochondrial, Lipoic acid-containing protein, GCSH
Antigen Type:
Recombinant Protein
Gene Name: GCSH (HGNC:4208)
Gene ID: 2653
NCBI Accession: NP_004474.2
Primary Accession: P23434
Other Accession: BC000790
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
Other Names:
Glycine cleavage system H protein, mitochondrial, Lipoic acid-containing protein, GCSH
Antigen Type:
Recombinant Protein
Gene Name: GCSH (HGNC:4208)
Gene ID: 2653
NCBI Accession: NP_004474.2
Primary Accession: P23434
Other Accession: BC000790
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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