GDA polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8219
Background:
The assembly of neurotransmitter receptors and associated signal transduction machinery at synaptic sites involves postsynaptic density 95 (PSD-95) and related membrane-associated guanylate kinase (MAGUK) proteins. Cypin, (Cytoplasmic PSD-95 interactor, also designated guanine deaminase and nedasin S), regulates intermediate steps in postsynaptic protein sorting, such as synaptic clustering of MAGUK proteins, and associates with multiple members of the PSD-95 family . Expressed both pre- and post-synaptically, cypin is most prevalent within the cytoplasm of dendritic shafts and in the neck of synaptic spines . In non-neuronal cells, cypin is most highly expressed in the basal membrane of intestinal epithelial cells. Cypin is also highly expressed in kidney, liver, lung, brain, and spleen, with lower levels of expression in placenta, heart, and skeletal muscle . Native cypin may also be expressed as a dimer and a tetramer .
Alternative Name:
CYPIN, Cytoplasmic PSD95 interactor, D10S105E, GAH, GDA, GUAD_HUMAN, Guanase, Guanine aminase, Guanine aminohydrolase, Guanine deaminase, MGC9982, NEDASIN, p51-nedasin, SLC25A16
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: GDA polyclonal antibody detects endogenous levels of GDA protein.
Immunogen:
Recombinant full length Human GDA.
MW: ~ 51 kDa
Swis Prot.: Q9Y2T3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The assembly of neurotransmitter receptors and associated signal transduction machinery at synaptic sites involves postsynaptic density 95 (PSD-95) and related membrane-associated guanylate kinase (MAGUK) proteins. Cypin, (Cytoplasmic PSD-95 interactor, also designated guanine deaminase and nedasin S), regulates intermediate steps in postsynaptic protein sorting, such as synaptic clustering of MAGUK proteins, and associates with multiple members of the PSD-95 family . Expressed both pre- and post-synaptically, cypin is most prevalent within the cytoplasm of dendritic shafts and in the neck of synaptic spines . In non-neuronal cells, cypin is most highly expressed in the basal membrane of intestinal epithelial cells. Cypin is also highly expressed in kidney, liver, lung, brain, and spleen, with lower levels of expression in placenta, heart, and skeletal muscle . Native cypin may also be expressed as a dimer and a tetramer .
Alternative Name:
CYPIN, Cytoplasmic PSD95 interactor, D10S105E, GAH, GDA, GUAD_HUMAN, Guanase, Guanine aminase, Guanine aminohydrolase, Guanine deaminase, MGC9982, NEDASIN, p51-nedasin, SLC25A16
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: GDA polyclonal antibody detects endogenous levels of GDA protein.
Immunogen:
Recombinant full length Human GDA.
MW: ~ 51 kDa
Swis Prot.: Q9Y2T3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review