GDF-3 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],online information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,

Synonyms: GDF3, Growth/differentiation factor 3, GDF-3

Gene Name: GDF3

Gene ID: 9573

SwissProt ID: Q9NR23

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.