GDF-5 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES4032
Catalog Number: ELK-ES4032
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
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Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
growth differentiation factor 5(GDF5) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016],
Alternative Names:
GDF5, CDMP1, Growth/differentiation factor 5, GDF-5, Cartilage-derived morphogenetic protein 1, CDMP-1, Radotermin
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF5. AA range:361-410
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 55
GeneID: GDF5
Storage: -20°C/1 year
NOTE: For Research Use Only
growth differentiation factor 5(GDF5) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016],
Alternative Names:
GDF5, CDMP1, Growth/differentiation factor 5, GDF-5, Cartilage-derived morphogenetic protein 1, CDMP-1, Radotermin
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF5. AA range:361-410
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 55
GeneID: GDF5
Storage: -20°C/1 year
NOTE: For Research Use Only
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