GDF15 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP2062a
Background:
GDF15 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF15 is highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
Other Names:
Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15, MIC1, PDF, PLAB, PTGFB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2062a was selected from the N-term region of human GDF15 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GDF15 {ECO:0000303|PubMed:23468844, ECO:0000312|HGNC:HGNC:30142}
Gene ID: 9518
Primary Accession: Q99988
Other Accession: GDF15_HUMAN
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
GDF15 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF15 is highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
Other Names:
Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15, MIC1, PDF, PLAB, PTGFB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2062a was selected from the N-term region of human GDF15 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GDF15 {ECO:0000303|PubMed:23468844, ECO:0000312|HGNC:HGNC:30142}
Gene ID: 9518
Primary Accession: Q99988
Other Accession: GDF15_HUMAN
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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