GDI1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5731
Background:
Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking. Rab GDP dissociation inhibitor (Rab GDI or GDI3) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP. In mammals, there exist two major isoforms, Rab GDI α (also known as XAP-4) and Rab GDI β. While the mammalian Rab GDI β-genes are ubiquitously expressed, the Rab GDI α genes are predominantly brain-specific. Since it is expressed predominantly in neural and sensory tissues, Rab GDI α may serve a specific function in neural signalmtransmission. The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms.
Alternative Name:
Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Rab GDI α, Rab GDIα, RabGDIα, Guanosine diphosphate dissociation inhibitor 1, GDI-1, Oligophrenin-2, Protein XAP-4, GDIL, OPHN2, RABGDIA, XAP4
Application Dilution: WB: 1:500~1:1000
Specificity: GDI1 polyclonal antibody detects endogenous levels of GDI1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 402-447 of Human GDI1.
MW: ~ 55 kDa
Swis Prot.: P31150
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking. Rab GDP dissociation inhibitor (Rab GDI or GDI3) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP. In mammals, there exist two major isoforms, Rab GDI α (also known as XAP-4) and Rab GDI β. While the mammalian Rab GDI β-genes are ubiquitously expressed, the Rab GDI α genes are predominantly brain-specific. Since it is expressed predominantly in neural and sensory tissues, Rab GDI α may serve a specific function in neural signalmtransmission. The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms.
Alternative Name:
Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Rab GDI α, Rab GDIα, RabGDIα, Guanosine diphosphate dissociation inhibitor 1, GDI-1, Oligophrenin-2, Protein XAP-4, GDIL, OPHN2, RABGDIA, XAP4
Application Dilution: WB: 1:500~1:1000
Specificity: GDI1 polyclonal antibody detects endogenous levels of GDI1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 402-447 of Human GDI1.
MW: ~ 55 kDa
Swis Prot.: P31150
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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