GDI2 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13787c
Background:
GDP dissociation inhibitors are proteins that regulate theGDP-GTP exchange reaction of members of the rab family, smallGTP-binding proteins of the ras superfamily, that are involved invesicular trafficking of molecules between cellular organelles.GDIs slow the rate of dissociation of GDP from rab proteins andrelease GDP from membrane-bound rabs. GDI2 is ubiquitouslyexpressed. The GDI2 gene contains many repetitive elementsindicating that it may be prone to inversion/deletionrearrangements. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.
Other Names:
Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2, GDI2, RABGDIB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13787c was selected from the Center region of GDI2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GDI2
Gene ID: 2665
Primary Accession: P50395
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
GDP dissociation inhibitors are proteins that regulate theGDP-GTP exchange reaction of members of the rab family, smallGTP-binding proteins of the ras superfamily, that are involved invesicular trafficking of molecules between cellular organelles.GDIs slow the rate of dissociation of GDP from rab proteins andrelease GDP from membrane-bound rabs. GDI2 is ubiquitouslyexpressed. The GDI2 gene contains many repetitive elementsindicating that it may be prone to inversion/deletionrearrangements. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.
Other Names:
Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2, GDI2, RABGDIB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13787c was selected from the Center region of GDI2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GDI2
Gene ID: 2665
Primary Accession: P50395
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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