GDNF polyclonal, anti-rat, human

Quantity: 100 µg

Background:
Glial cell line-derived neurotrophic factor(GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. GDNF is also a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures. In addition to its potential role in the differentiation and survival of central nervous system neurons, it has profound effects on kidney organogenesis and the development of the peripheral nervous system. GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.

Description:
Rabbit IgG polyclonal antibody for Glial cell line-derived neurotrophic factor (GDNF) detection. Tested with WB in Human, Rat.

Synonyms:
gdnf antibody, GDNF_HUMAN antibody, Glial cell derived neurotrophic factor antibody, Glial Cell Line Derived Neurotrophic Factor antibody, Glial cell line-derived neurotrophic factor antibody, Glial derived neurotrophic factor antibody, HFB1 GDNF antibody, hGDNF antibody, HSCR3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human GDNF recombinant protein (Position: S78-I211). Human GDNF shares 93% amino acid (aa) sequence identity with both mouse and rat GDNF.E.coli-derived human GDNF recombinant protein (Position: S78-I211). Human GDNF shares 93% amino acid (aa) sequence identity with both mouse and rat GDNF.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.