GDNF polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP8680A
Catalog Number: AC-AP8680A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21995
Applications: FC, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21995
Applications: FC, IHC-P
Datasheet
Request Information
Background:
GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described.
Other Names:
Glial cell line-derived neurotrophic factor, hGDNF, Astrocyte-derived trophic factor, ATF, GDNF
Target/Specificity:
This GDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human GDNF.
Antigen Region:
8-36
Antigen Type: Synthetic Peptide
Gene Name: GDNF
Gene ID: 2668
Primary Accession: P39905
NCBI Accession: NP_000505.1;NP_001177397.1;NP_001177398.1;NP_001265027.1;NP_954701.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described.
Other Names:
Glial cell line-derived neurotrophic factor, hGDNF, Astrocyte-derived trophic factor, ATF, GDNF
Target/Specificity:
This GDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human GDNF.
Antigen Region:
8-36
Antigen Type: Synthetic Peptide
Gene Name: GDNF
Gene ID: 2668
Primary Accession: P39905
NCBI Accession: NP_000505.1;NP_001177397.1;NP_001177398.1;NP_001265027.1;NP_954701.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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