Gelsolin (clone GS-2C4), anti-human
€455.00
In stock
SKU
AC-ABO10434
Catalog Number: AC-ABO10434
Size: 100 µg
Isotype: Mouse IgG
Applications: WB, IHC-P, IHC-F
Datasheet
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Size: 100 µg
Isotype: Mouse IgG
Applications: WB, IHC-P, IHC-F
Datasheet
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Description: Mouse IgG monoclonal antibody for Gelsolin, gelsolin (GSN) detection. Tested with WB, IHC-P, IHC-F in Human; rabbit. No cross reactivity with other proteins.Protein Name: Gelsolin
Protein Function:
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis (By similarity). .
Other Names: Gelsolin, Actin-depolymerizing factor, ADF, Brevin, Gsn
Clone Name(s):
GS-2C4
Subcellular Localization: Isoform 1: Secreted .
Tissue Specificity: GSN: Phagocytic cells, platelets, fibroblasts,nonmuscle cells, smooth and skeletal muscle cells.
Gene ID: 296654
Immunogen: Human plasma gelsolin.
Calculated MW: 86068
Purification: Ascites
Format: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Concentration (mg/ml): Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis (By similarity). .
Other Names: Gelsolin, Actin-depolymerizing factor, ADF, Brevin, Gsn
Clone Name(s):
GS-2C4
Subcellular Localization: Isoform 1: Secreted .
Tissue Specificity: GSN: Phagocytic cells, platelets, fibroblasts,nonmuscle cells, smooth and skeletal muscle cells.
Gene ID: 296654
Immunogen: Human plasma gelsolin.
Calculated MW: 86068
Purification: Ascites
Format: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Concentration (mg/ml): Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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