GEMIN2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Synonyms: SIP1, SIP1-delta

Cellular Location: Cytoplasm Nucleus gem

Immunogen:
A synthetic peptide of human GEMIN2

Gene Symbol: GEMIN2

Gene ID: 8487

Swiss prot: O14893

Calculated MW: 32kDa

Recommended dilution:
WB 1:500-1000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.