Gephyrin polyclonal, anti-human, mouse, rat

Background:
The sub-membraneous region at the postsynaptic membrane contains a number of proteins critical for receptor targeting. Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue.

Alternative Name:
MPT adenylyltransferase, MPT Mo-transferase, GPHN, GPH, KIAA1385, Domain E, Domain G, GEPH, GEPH, GPH, GPHN, GPHRYN, KIAA1385, Molybdopterin molybdenumtransferase, MPT adenylyltransferase, MPT Mo-transferase,

Application Dilution:
WB:1:500-1:2,000
IHC:1:50-1:200

Specificity: Gephyrin polyclonal antibody detects endogenous levels of Gephyrin protein.

MW: 80 kDa

Swiss-Prot: Q9NQX3(Human) Q03555(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.