GFAP (+1) polyclonal, anti-human

Quantity: 100 µl

Background:
GFAP +1 is an out-of-frame splice variant of GFAP, resulting in a protein with a shortened coil 2B, which is selectively loCated in degeneRative neurons. Normally, GFAPs are loCated in astrocytes and represent the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the proliferation of astrocytes which occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer's disease, epilepsy and multiple sclerosis.

Isotype: Rabbit Polyclonal

Source: GFAP +1 is a Rabbit polyclonal anti-serum derived by immunization with the peptide DRGDAGWRGH, representing the last 10 C-terminal amino acids encoded by out-of-frame splice variants (? 164 nt, ? exon 6).

Form: Each vial contains 100 ul Rabbit polyclonal Serum containing 0.09% sodium azide.

Reactivity: human

Applications: Immunohistochemistry (frozen), Western blotting

Storage: Store at 4C, or in small aliquots at -20C.