GFAP (K39) polyclonal, anti-human, mouse, rat, zebrafish

Quantity: 100 µl

Background:
GFAP (55 kD) is selectively loCated in astrocytes and represents the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the proliferation of astrocytes that occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer's disease, epilepsy and multiple sclerosis. In the peripheral nervous system GFAP is expressed by Schwann cells. Upon differentiation, myelin forming Schwann cells down-regulate GFAP, whereas in non-myelin forming Schwann cells GFAP persists into adulthood.

Isotype: Rabbit Polyclonal

Source: K39 is a Rabbit polyclonal anti-serum derived by immunization of a Rabbit with a glial fibrillary acidic protein prepaRation from Human spinal cord.

Form: Each vial contains 100 ul Rabbit polyclonal Serum containing 0.09% sodium azide.

Reactivity: human, mouse, rat, Zebrafish

Applications: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western blotting

Storage: Store at 4C, or in small aliquots at -20C.