GFI1 antibody (clone 3G8), anti-human
€435.00
In stock
SKU
AC-AT2193a
Catalog Number: AC-AT2193a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT2193a">Request Information
Background:
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Other Names:
Zinc finger protein Gfi-1, Growth factor independent protein 1, Zinc finger protein 163, GFI1, ZNF163
Antigen Type:
Recombinant Protein
Gene Name: GFI1
Gene ID: 2672
NCBI Accession: NP_001120687.1;NP_001120688.1;NP_005254.2
Primary Accession: Q99684
Other Accession: NM_005263
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Other Names:
Zinc finger protein Gfi-1, Growth factor independent protein 1, Zinc finger protein 163, GFI1, ZNF163
Antigen Type:
Recombinant Protein
Gene Name: GFI1
Gene ID: 2672
NCBI Accession: NP_001120687.1;NP_001120688.1;NP_005254.2
Primary Accession: Q99684
Other Accession: NM_005263
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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