GFRA1 antibody (clone 30000), anti-human
€435.00
In stock
SKU
AC-AT2194a
Catalog Number: AC-AT2194a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
Request Information AC-AT2194a">Request Information
Background:
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
Other Names:
GDNF family receptor alpha-1, GDNF receptor alpha-1, GDNFR-alpha-1, GFR-alpha-1, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1, GFRA1, GDNFRA, RETL1, TRNR1
Antigen Type:
Recombinant Protein
Gene Name: GFRA1
Gene ID: 2674
NCBI Accession: NP_001138925.1;NP_005255.1;NP_665736.1
Primary Accession: P56159
Other Accession: NM_005264
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
Other Names:
GDNF family receptor alpha-1, GDNF receptor alpha-1, GDNFR-alpha-1, GFR-alpha-1, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1, GFRA1, GDNFRA, RETL1, TRNR1
Antigen Type:
Recombinant Protein
Gene Name: GFRA1
Gene ID: 2674
NCBI Accession: NP_001138925.1;NP_005255.1;NP_665736.1
Primary Accession: P56159
Other Accession: NM_005264
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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