GFRA3 Polyclonal Antibody

Background:
GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.

Research Area: Cancer, Neuroscience

Synonyms:
GDNF family receptor alpha 3, GDNF family receptor alpha-3, GDNF receptor alpha-3, GDNFR-alpha-3, GDNFR3, GFR-alpha-3, GFRA3, GFRA3, Glial cell line derived neurotrophic factor receptor alpha 3, GPI linked receptor, OTTHUMP00000159486, OTTHUMP00000224020

Immunogen: Synthetic peptide of human GFRA3

Swissprot: O60609
Gene Accession: NP_001487

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:150

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9340/sc-28954