Gγ 5 rabbit polyclonal, anti-human, mouse, rat

Backgroud: G protein subunit gamma 5(GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010],function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma.,

Synonyms: GNG5, GNGT5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5

Gene Name: GNG5

Gene ID: 2787

SwissProt ID: P63218

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.