GGA2 Polyclonal Antibody
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In stock
SKU
E-AB-60241
Catalog Number: E-AB-60241
Isotype: Rabbit IgG
Reactivity: human, mouse
Applications: IHC,IF
Datasheet, Questions? Contact us!
Isotype: Rabbit IgG
Reactivity: human, mouse
Applications: IHC,IF
Datasheet, Questions? Contact us!
Background:
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Research Area: Signal Transduction
Synonyms:
GGA2, VEAR
Immunogen: Recombinant fusion protein of human GGA2 (NP_055859.1).
Swissprot: Q9UJY4
Gene ID: 23062
Purification Method: Affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Research Area: Signal Transduction
Synonyms:
GGA2, VEAR
Immunogen: Recombinant fusion protein of human GGA2 (NP_055859.1).
Swissprot: Q9UJY4
Gene ID: 23062
Purification Method: Affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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