GGCX polyclonal (Center), anti-human

GGCX polyclonal (Center), anti-human

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In stock
SKU
AC-AP11117c
Catalog Number: AC-AP11117c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19281
Applications: WB, IHC-P
Datasheet

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Background:
This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Other Names:
Vitamin K-dependent gamma-carboxylase, Gamma-glutamyl carboxylase, Peptidyl-glutamate 4-carboxylase, Vitamin K gamma glutamyl carboxylase, GGCX, GC

Target/Specificity:
This GGCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-578 amino acids from the Central region of human GGCX.

Antigen Region:
548-578

Antigen Type: Synthetic Peptide

Gene Name: GGCX
Gene ID: 2677
Primary Accession: P38435
NCBI Accession: NP_000812.2;NP_001135741.1
Other Accession: O88496; NP_000812.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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