GGT1 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain| which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22| and putative pseudogenes for this gene on chromosomes 2| 13| and 22.

Research Area: Metabolism, Signal transduction

Synonyms: GGT1 , light chain, Cleaved-Thr381, Gamma-glutamyltranspeptidase 1, GGT 1, EC 2.3.2.2, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, EC 3.4.19.13, Leukotriene-C4 hydrolase, EC 3.4.19.14, CD antigen CD224, Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain,

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year