GH2 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP16456a
Catalog Number: AC-AP16456a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26211
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26211
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq].
Other Names:
Growth hormone variant, GH-V, Growth hormone 2, Placenta-specific growth hormone, GH2
Target/Specificity:
This GH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human GH2.
Antigen Region:
19-45
Antigen Type: Synthetic Peptide
Gene Name: GH2
Gene ID: 2689
Primary Accession: P01242
NCBI Accession: NP_002050.1;NP_072050.1;NP_072051.1;NP_072052.1
Other Accession: NP_002050.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq].
Other Names:
Growth hormone variant, GH-V, Growth hormone 2, Placenta-specific growth hormone, GH2
Target/Specificity:
This GH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human GH2.
Antigen Region:
19-45
Antigen Type: Synthetic Peptide
Gene Name: GH2
Gene ID: 2689
Primary Accession: P01242
NCBI Accession: NP_002050.1;NP_072050.1;NP_072051.1;NP_072052.1
Other Accession: NP_002050.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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