GHR Polyclonal Antibody

Background:
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.

Research Area: Cancer, Cell biology, Developmental biology, Signal transduction

Synonyms:
GH receptor, GH-binding protein, GHBP, GHBP, included, GHR, GHR, Growth hormone binding protein, Growth hormone receptor, Growth hormone receptor precursor, Growth hormone-binding protein, Growth hormone-binding protein, included, Increased responsiveness to growth hormone, included, Serum binding protein, Serum-binding protein, Somatotropin receptor

Immunogen: Synthetic peptide of human GHR

Swissprot: P10912
Gene Accession: NP_000154

Calculated MW: 72 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-2000, ELISA 1:2000-5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20747