Ghrelin Peptide

Ghrelin Peptide

€315.00
In stock
SKU
350193
Catalog Number: 350193
Size: 1 mg
Datasheet
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Protein Family: Hormones

Pathway and Disease: Lipid Metabolism, Metabolic Disorders, Signal Transduction, Signaling Molecules and Interaction

Alternate Names: Ghrelin; appetite-regulating hormone; growth hormone secretagogue; growth hormone-releasing peptide; motilin-related peptide; M46 protein; ghrelin-28; GHRL; MTLRP; GHRP

Accession No.: Q9UBU3

Description:
Ghrelin (also called Ghrelin-28) is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Ghrelin induces the release of growth hormone from the pituitary gland. Ghrelin has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. The 117-aa Ghrelin precursor, the growth hormone-releasing peptide (GHRP), is cleaved into 3 chains: Ghrelin-27 (27 aa), Ghrelin-28 (28 aa) and obestatin (23 aa). Ghrelin-28 is a 28-aa peptide modified by O-octanoylation or O-decanoylation essential for activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. Cat. No. 350193 corresponds to the Ghrelin-28-C8 form.

Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

MW: 3371.3 g/mol

Sequence:
Human: H-Gly-Ser-Ser(octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH or H-GSS(octanoyl)FLSPEHQRVQQRKESKKPPAKLQPR-OH

Composition:
C149H249N47O42

Purity:
> 95% by HPLC

Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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