GHRH polyclonal (N-term), anti-human

GHRH polyclonal (N-term), anti-human

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In stock
SKU
AC-AP7758A
Catalog Number: AC-AP7758A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14533
Applications: WB, IHC-P, IF
Datasheet

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Background:
GHRH belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this protein are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.

Other Names:
Somatoliberin, Growth hormone-releasing factor, GRF, Growth hormone-releasing hormone, GHRH, Somatocrinin, Somatorelin, Sermorelin, GHRH, GHRF

Target/Specificity:
This GHRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-34 amino acids from the N-terminal region of human GHRH.

Antigen Region:
8-34

Antigen Type: Synthetic Peptide

Gene Name: GHRH
Gene ID: 2691
Primary Accession: P01286
NCBI Accession: NP_001171660.1;NP_066567.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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