GHSR polyclonal (C-term), anti-human, mouse
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In stock
SKU
AC-AP11873b
Catalog Number: AC-AP11873b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18124
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18124
Applications: WB, IHC-P
Datasheet
Request Information
Background:
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Other Names:
Growth hormone secretagogue receptor type 1, GHS-R, GH-releasing peptide receptor, GHRP, Ghrelin receptor, GHSR
Target/Specificity:
This GHSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-357 amino acids from the C-terminal region of human GHSR.
Antigen Region:
326-357
Antigen Type: Synthetic Peptide
Gene Name: GHSR
Gene ID: 2693
Primary Accession: Q92847
NCBI Accession: NP_004113.1;NP_940799.1
Other Accession: A5A4K9; Q95254; NP_940799
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Other Names:
Growth hormone secretagogue receptor type 1, GHS-R, GH-releasing peptide receptor, GHRP, Ghrelin receptor, GHSR
Target/Specificity:
This GHSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-357 amino acids from the C-terminal region of human GHSR.
Antigen Region:
326-357
Antigen Type: Synthetic Peptide
Gene Name: GHSR
Gene ID: 2693
Primary Accession: Q92847
NCBI Accession: NP_004113.1;NP_940799.1
Other Accession: A5A4K9; Q95254; NP_940799
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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