GIP (Gastric Inhibitory Peptide) polyclonal, anti-human, pig, rat

Quantity: 50 µl

Background:
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.

Synonyms:
GIP

Isotype: Rabbit Polyclonal

Immunogen:
Pure Porcine GIP

Form: Serum containing 0.1% sodium azide

Specificity:
GIP (Gastric Inhibitory Peptide)

Reactivity: human, pig, rat

Applications: Immunofluorescence, Immunohistochemistry on paraffin and frozen sections

Working DIlution: 1:40-1:100 (PAP); 1:20 - 1:60 using immunofluorescence (FITC)

Positive Control:
Frozen sections of pig small intestine

Storage: 2-8C for immediate use, or at -20C (aliquot)

References:
- Portela-Gomes G. et al. (1997) J. Histochem. & Cytochem. 45: 815-822