GIPR polyclonal, anti-human, mouse

Background:
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

Synonyms: PGQTL2

Cellular Location: Cell membrane Multi-pass membrane protein

Immunogen:
A synthetic peptide of human GIPR

Gene Symbol: GIPR

Gene ID: 2696

Swiss prot: P48546

Calculated MW: 53 kDa

Recommended dilution:
WB 1:200-1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.