GIPR polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71333
Background:
GIPR (gastric inhibitory polypeptide receptor) is a 466 amino acid protein belonging to the G-protein coupled receptor 2 family. The activity of GIPR is mediated by G proteins, which activate adenylyl cyclase. Expressed as two isoforms produced by alternative splicing, GIPR is a multi-pass cell membrane protein that acts as a receptor for the glucose-dependent insulinotropic polypeptide (GIP). GIP is a major physiologic factor in the augmentation of the insulin response to oral glucose. GIP is a peptide hormone that is released postprandially from the small intestine and acts in concert with glucagon-like peptide (GLP)-1 to potentiate glucose-induced insulin secretion from the pancreatic beta-cell.
Alternative Name:
Gastric inhibitory polypeptide receptor, GIP-R
Application Dilution: WB: 1:200 - 1:500
Specificity: GIPR polyclonal antibody detects endogenous levels of GIPR protein.
Immunogen:
Recombinant protein of human GIPR.
MW: ~ 53 kDa
Swis Prot.: P48546
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
GIPR (gastric inhibitory polypeptide receptor) is a 466 amino acid protein belonging to the G-protein coupled receptor 2 family. The activity of GIPR is mediated by G proteins, which activate adenylyl cyclase. Expressed as two isoforms produced by alternative splicing, GIPR is a multi-pass cell membrane protein that acts as a receptor for the glucose-dependent insulinotropic polypeptide (GIP). GIP is a major physiologic factor in the augmentation of the insulin response to oral glucose. GIP is a peptide hormone that is released postprandially from the small intestine and acts in concert with glucagon-like peptide (GLP)-1 to potentiate glucose-induced insulin secretion from the pancreatic beta-cell.
Alternative Name:
Gastric inhibitory polypeptide receptor, GIP-R
Application Dilution: WB: 1:200 - 1:500
Specificity: GIPR polyclonal antibody detects endogenous levels of GIPR protein.
Immunogen:
Recombinant protein of human GIPR.
MW: ~ 53 kDa
Swis Prot.: P48546
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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