GIPR polyclonal antibody, anti-human
€0.00
In stock
SKU
BT-AP03569
Catalog Number: BT-AP03569
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human
Application(s): WB, IHC-p, IF, ELISA
Datasheet
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Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human
Application(s): WB, IHC-p, IF, ELISA
Datasheet
Request Information
Background:
GIPR encodes Gastric inhibitory polypeptide receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking GIPR exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in GIPR thus may contribute to the pathogenesis of diabetes.
Research Area: Neuroscience
Synonyms: GIPR, Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
GIPR encodes Gastric inhibitory polypeptide receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking GIPR exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in GIPR thus may contribute to the pathogenesis of diabetes.
Research Area: Neuroscience
Synonyms: GIPR, Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
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