GIPR polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP7495c
Catalog Number: AC-AP7495c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18126
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18126
Applications: WB
Datasheet
Request Information
Background:
GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
Other Names:
Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, GIPR
Target/Specificity:
This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-136 amino acids from the Central region of human GIPR.
Antigen Region:
104-136
Antigen Type: Synthetic Peptide
Gene Name: GIPR
Gene ID: 2696
Primary Accession: P48546
NCBI Accession: NP_000155.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
Other Names:
Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, GIPR
Target/Specificity:
This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-136 amino acids from the Central region of human GIPR.
Antigen Region:
104-136
Antigen Type: Synthetic Peptide
Gene Name: GIPR
Gene ID: 2696
Primary Accession: P48546
NCBI Accession: NP_000155.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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