GJA3 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP1543a
Catalog Number: AC-AP1543a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1371
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1371
Applications: WB, IHC-P
Datasheet
Request Information
Background:
GJA3, an integral membrane protein, belong to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and nonjunctional ('hemi-') channels. Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3), a form of autosomal dominant congenital cataract.
Other Names:
Gap junction alpha-3 protein, Connexin-46, Cx46, GJA3
Target/Specificity:
This GJA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-139 amino acids from the N-terminal region of human GJA3.
Antigen Region:
108-139
Antigen Type: Synthetic Peptide
Gene Name: GJA3
Gene ID: 2700
Primary Accession: Q9Y6H8
NCBI Accession: NP_068773.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
GJA3, an integral membrane protein, belong to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and nonjunctional ('hemi-') channels. Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3), a form of autosomal dominant congenital cataract.
Other Names:
Gap junction alpha-3 protein, Connexin-46, Cx46, GJA3
Target/Specificity:
This GJA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-139 amino acids from the N-terminal region of human GJA3.
Antigen Region:
108-139
Antigen Type: Synthetic Peptide
Gene Name: GJA3
Gene ID: 2700
Primary Accession: Q9Y6H8
NCBI Accession: NP_068773.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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