GJB2 / Connexin 26 polyclonal, anti-mouse

Background:
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.

Other Names:
Gap junction beta-2 protein, Connexin-26, Cx26, GJB2

Antigen Types:
Synthetic Peptide

Gene Name:
GJB2
Gene ID:
2706
Primary Accession: P29033
Other Accession: NP_003995;2706;14619 (mouse); 394266 (rat);