GJB5 Antibody (Center) Blocking Peptide

Background:
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) such as GJB5 are thought to play crucial functional roles associated with these channels.

Other Names:
Gap junction beta-5 protein, Connexin-311, Cx311, GJB5

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1545b was selected from the center region of human GJB5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: GJB5

Gene ID: 2709
Primary Accession: O95377
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.