GJB6 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1546b
Background:
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.
Other Names:
Gap junction beta-6 protein, Connexin-30, Cx30, GJB6
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1546b was selected from the C-term region of human GJB6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GJB6
Gene ID: 10804
Primary Accession: O95452
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.
Other Names:
Gap junction beta-6 protein, Connexin-30, Cx30, GJB6
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1546b was selected from the C-term region of human GJB6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GJB6
Gene ID: 10804
Primary Accession: O95452
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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