GJB6 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP1546a
Catalog Number: AC-AP1546a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1391
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1391
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.
Other Names:
Gap junction beta-6 protein, Connexin-30, Cx30, GJB6
Target/Specificity:
This GJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-117 amino acids from the N-terminal region of human GJB6.
Antigen Region:
87-117
Antigen Type: Synthetic Peptide
Gene Name: GJB6
Gene ID: 10804
Primary Accession: O95452
NCBI Accession: NP_001103689.1;NP_001103690.1;NP_001103691.1;NP_006774.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.
Other Names:
Gap junction beta-6 protein, Connexin-30, Cx30, GJB6
Target/Specificity:
This GJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-117 amino acids from the N-terminal region of human GJB6.
Antigen Region:
87-117
Antigen Type: Synthetic Peptide
Gene Name: GJB6
Gene ID: 10804
Primary Accession: O95452
NCBI Accession: NP_001103689.1;NP_001103690.1;NP_001103691.1;NP_006774.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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