GKN1 Polyclonal Antibody

Background:
Gastrokine 1 (GKN1), a stomach-specic protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin, belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach, but is absent from gastric adenocarcinomas, gastro-esophageal adenocarcinoma cell lines, and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.

Research Area: Tags and Cell Markers

Synonyms:
18 kDa antrum mucosa protein, AMP 18, AMP-18, AMP18, Antrum mucosa protein, 18-KD, BRICD 1, BRICD1, BRICHOS domain containing 1, CA 11, CA11, CA11 gene, CA11 protein, FOV, Foveolin, Gastrokine-1, Gastrokine1, GKN 1, Gkn1, GKN1, MGC70354, Protein CA11, UNQ489/PRO1005

Immunogen: Synthetic peptide of human GKN1

Swissprot: Q9NS71
Gene Accession: NP062563

Calculated MW: 22 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.