GLDC polyclonal, anti-human, mouse

Background:
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Synonyms: GCE, GCSP, HYGN1

Cellular Location: Mitochondrion

Immunogen:
Recombinant protein of human GLDC

Gene Symbol: GLDC

Gene ID: 2731

Swiss prot: P23378

Calculated MW: 113kDa

Recommended dilution:
WB 1:200-500, IHC 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.