GLDC Polyclonal Antibody

Background:
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
GLDC, GCE, GCSP, HYGN1

Immunogen: Recombinant fusion protein of human GLDC (NP_000161.2).

Swissprot: P23378
Gene ID: 2731

Calculated MW: 112 kDa
Observed MW: 113 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.