Gli1 monoclonal, anti-human

Gli1 monoclonal, anti-human

€455.00
In stock
SKU
AC-ABO13436
Catalog Number: AC-ABO13436
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB
Datasheet
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Description: Anti-Gli1 Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human.

Protein Function:
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation..

Other Names: Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI, GLI1, GLI

Clone Name(s):
Clone: GCG-7

Subcellular Localization: Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.

Tissue Specificity: Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract..

Gene ID: 2735

Immunogen: A synthesized peptide derived from human Gli1

Calculated MW: 117904

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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