Glial filament protein polyclonal, anti-human, bovine, rat

Quantity: 25 µl

Background:
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Synonyms:
GFAP, GFP

Isotype: Guinea Pig Polyclonal

Immunogen:
Glialfilament protein purified from bovine spinal cord

Form: Stabilized Serum

Specificity:
Specific detection of gliafilament protein (Mr 52000 polypeptide). Tumors Specifically detected: Astrocytomas, gangliomas, meulloblastomas, certain teratomas.

Reactivity: human, bovine, rat

Applications: Immunohistochemistry on frozen & paraffin (P) sections, Immunoblotting (Western), Cytological material

Working DIlution: Frozen section: 1:100; Paraffin embedded Tissue: 1:50; Western Blotting: 1:2000

Storage: 2-8C

References:
- Gould VE et al. (1990) Am J Pathol 137: 1143-1155