GLP-2 polyclonal, anti-human, mouse, rat, pig, sheep, bovine

Protein Family: Hormones, Receptors and Channels, Enzymes

Pathway and Disease: Cell Motility, Endocrine System, Metabolic Disorders, Cell Growth and Death, Carbohydrate Metabolism, Energy Metabolism, Signaling Molecules and Interaction, Nervous and Sensory Systems

Description:
Glucagon-like peptide-2 (GLP-2) is a 33-aa peptide corresponding to aa146-178 of glucagon. GLP-2 is liberated in the intestinal L cells after glucagon processing. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract from the stomach to the colon is the principal target for the GLP-2 action. GLP-2 plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function as well as increasing nutrient disposal. GLP-2 also stimulates intestinal glucose transport and decreases mucosal permeability.

Alternate Names: Glucagon, Glucagon-like peptide 2, GLP-2, GCG, GLP2

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P01275

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GLP-2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.