GLP1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue. It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

Description:
Rabbit IgG polyclonal antibody for Glucagon (GCG) detection. Tested with IHC-P in Human, Mouse, Rat.

Synonyms:
GCG antibody, glicentin-related polypeptide antibody, GLP-1 antibody, GLP-1(7-36) antibody, GLP-1(7-37) antibody, GLP-2 antibody, GLP1 antibody, GLP1, included antibody, GLP2 antibody, GLP2, included antibody, GLUC_HUMAN antibody, Glucagon antibody, Glucagon like peptide 1 antibody, glucagon-like peptide 1 antibody, Glucagon-like peptide 1, included antibody, Glucagon-like peptide 2 antibody, Glucagon-like peptide 2, included antibody, GRPP antibody, OXM antibody, OXY antibody, preproglucagon antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human GLP1 (53-81aa HSQGTFTSDYSKYLDSRRAQDFVQWLMNT), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.