GLP1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP5500c
Catalog Number: AC-AP5500c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26991
Applications: FC, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26991
Applications: FC, WB
Datasheet
Request Information
Background:
Glucagon is initially synthesised as proglucagon, which is 180 amino acids in length and is cleaved proteolytically. It contains a region corresponding to Glucagon itself, in addition to a signal peptide, spacer regions and two Glucagon-like peptide sequences. GLP1 is encoded by the fourth exon of the six in the human Glucagon gene. It is 37 amino acids in length and has 48% amino acid sequence homology to Glucagon, and is thought to have arisen by gene duplication. The sequence of GLP1 is conserved across many species, however, indicating that it has a particular function. GLP1 is a potent insulin secretagogue, renders pancreatic beta cells 'glucose-competent' and may be useful in the treatment of diabetes mellitus.
Other Names:
GATA-type zinc finger protein 1, GATA-like protein 1, GLP-1, ZGLP1, GLP1
Target/Specificity:
This GLP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-112 amino acids from the Central region of human GLP1.
Antigen Region:
85-112
Antigen Type: Synthetic Peptide
Gene Name: ZGLP1 (HGNC:37245)
Gene ID: 100125288
Primary Accession: P0C6A0
NCBI Accession: NP_001096637.1
Other Accession: NP_001096637.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Glucagon is initially synthesised as proglucagon, which is 180 amino acids in length and is cleaved proteolytically. It contains a region corresponding to Glucagon itself, in addition to a signal peptide, spacer regions and two Glucagon-like peptide sequences. GLP1 is encoded by the fourth exon of the six in the human Glucagon gene. It is 37 amino acids in length and has 48% amino acid sequence homology to Glucagon, and is thought to have arisen by gene duplication. The sequence of GLP1 is conserved across many species, however, indicating that it has a particular function. GLP1 is a potent insulin secretagogue, renders pancreatic beta cells 'glucose-competent' and may be useful in the treatment of diabetes mellitus.
Other Names:
GATA-type zinc finger protein 1, GATA-like protein 1, GLP-1, ZGLP1, GLP1
Target/Specificity:
This GLP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-112 amino acids from the Central region of human GLP1.
Antigen Region:
85-112
Antigen Type: Synthetic Peptide
Gene Name: ZGLP1 (HGNC:37245)
Gene ID: 100125288
Primary Accession: P0C6A0
NCBI Accession: NP_001096637.1
Other Accession: NP_001096637.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review