GLRA1 Polyclonal Antibody

Background:
The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Three transcript variants encoding different isoforms have been found for this gene.

Research Area: Neuroscience

Synonyms:
GLRA1, GLRA1, Glycine receptor 48 kDa subunit, Glycine receptor alpha 1, Glycine receptor strychnine-binding subunit, Glycine receptor subunit alpha-1, Glycine receptor, alpha 1 subunit, HKPX1, STHE

Immunogen: Synthetic peptide of human GLRA1

Swissprot: P23415
Gene Accession: NP_000162

Calculated MW: 53 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-2000, IHC 1:10-50, ELISA 1:2000-5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-17278/sc-133629/sc-33611