GLRB polyclonal (N-term), anti-human
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In stock
SKU
AC-AP14931a
Catalog Number: AC-AP14931a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35424
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35424
Applications: WB
Datasheet
Request Information
Background:
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
Other Names:
Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, GLRB
Target/Specificity:
This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.
Antigen Region:
103-132
Antigen Type: Synthetic Peptide
Gene Name: GLRB
Gene ID: 2743
Primary Accession: P48167
NCBI Accession: NP_000815.1;NP_001159532.1;NP_001159533.1
Other Accession: P20781; P48168; Q9GJS9; NP_001159532.1; NP_000815.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
Other Names:
Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, GLRB
Target/Specificity:
This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.
Antigen Region:
103-132
Antigen Type: Synthetic Peptide
Gene Name: GLRB
Gene ID: 2743
Primary Accession: P48167
NCBI Accession: NP_000815.1;NP_001159532.1;NP_001159533.1
Other Accession: P20781; P48168; Q9GJS9; NP_001159532.1; NP_000815.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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