GLS polyclonal (C-term), anti-human, mouse, rat

GLS polyclonal (C-term), anti-human, mouse, rat

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In stock
SKU
AC-AP8809b
Catalog Number: AC-AP8809b
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB22875
Applications: WB, IHC-P-Leica, IF, FC
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Background:
Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.

Other Names:
Glutaminase kidney isoform, mitochondrial, GLS, K-glutaminase, L-glutamine amidohydrolase, GLS, GLS1, KIAA0838

Target/Specificity:
This GLS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human GLS.

Antigen Region:
516-545

Antigen Type: Synthetic Peptide

Gene Name: GLS
Gene ID: 2744
Primary Accession: O94925
NCBI Accession: NP_001243239.1;NP_055720.3
Other Accession: P13264; D3Z7P3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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