Glucagon polyclonal (C-term), anti-human

Glucagon polyclonal (C-term), anti-human

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In stock
SKU
AC-AP6798C
Catalog Number: AC-AP6798C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19525
Applications: IF, WB, FC, IHC-P-Leica
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Background:
Glucagon is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Other Names:
Glucagon, Glicentin, Glicentin-related polypeptide, GRPP, Oxyntomodulin, OXM, OXY, Glucagon, Glucagon-like peptide 1, GLP-1, Incretin hormone, Glucagon-like peptide 1(7-37), GLP-1(7-37), Glucagon-like peptide 1(7-36), GLP-1(7-36), Glucagon-like peptide 2, GLP-2, GCG

Target/Specificity:
This Glucagon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human Glucagon.

Antigen Region:
119-148

Antigen Type: Synthetic Peptide

Gene Name: GCG (HGNC:4191)
Gene ID: 2641
Primary Accession: P01275
NCBI Accession: NP_002045.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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